A First-in-human Safety Trial of BNT331 Administered as Single Ascending Doses in Healthy Women and as Multiple Ascending Doses in Women Diagnosed With Bacterial Vaginosis

Completed · Phase 1 · Has a placebo group

Conditions studied: Bacterial Vaginosis

In brief

This is a two-part, randomized, double-blind, placebo-controlled study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy (for Part B) of BNT331 in healthy women (Part A) and in women diagnosed with bacterial vaginosis (BV) (Part B).

Key facts

Study ID
NCT06469164
Run by
BioNTech SE
People needed
102
Starts
2024-07-01
Expected to finish
2025-07-31
Last updated by the study team
2025-08-07

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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