GDFT on the Postoperative Outcome in Head and Neck Cancer Surgery
Recruiting now · Not applicable
Conditions studied: Postoperative Complications
In brief
The goal of this clinical trial is to evaluate whether goal-directed fluid therapy (GDFT) can improve the postoperative recovery in patients undergoing head and neck cancer surgery. It aims to answer is: • Whether GDFT can reduce the occurrence of serious postoperative complications? Researchers will compare GDFT protocol to a standard conventional fluid therapy in head and neck cancer surgery to see if GDFT strategy works to improve the postoperative recovery. Participants will * Receive GDFT protocol or a conventional fluid therapy during the surgery. * Be continuously follow-up during hospitalization and after discharge to record the occurrence of postoperative complications.
Key facts
- Study ID
- NCT06468852
- Run by
- Beijing Tongren Hospital
- People needed
- 340
- Starts
- 2024-05-16
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2024-06-21
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult patients (Age≥18)
- Scheduled to undergo head and neck cancer surgery (including nasopharyngeal carcinoma, laryngocarcinoma, hypopharyngeal carcinoma, and other head and neck malignancies, but not thyroid cancer) with an expected duration of 2 hours or longer
- Agree to receive invasive artery blood pressure monitoring
You may not qualify if…
- American Society of Anesthesiologists (ASA) classification>Ⅳ
- Palliative surgery was performed for the terminal tumors
- Microlaryngoscopic laser surgery or endoscopic surgery
- Underwent major thoracic or abdominal surgery within 30 days
- Regular renal replacement therapy is required
- NYHA grade>3 or ejection fraction <30%
- Lung disease does not tolerate the tidal volume by 8 ml/kg
- Atrial fibrillation
- Unable to give informed consent
- pregnant or lactating woman
- Emergency surgery
Where it is running
- Beijing tongren Hospital, Capital Medical University — Beijing, Beijing Municipality, China (enrolling)
Full record on ClinicalTrials.gov
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