Understanding the Acute Pain Phenotype in Patients Undergoing Surgery

Recruiting now

Conditions studied: Acute Pain, Chronic Post Operative Pain, Opioid Use

In brief

The goal of this observational study is to learn about how regional anesthesia (numbing medication) affects pain in patients with different psychosocial phenotypes such as different levels of concern about pain, sleep issues, and anxiety, who are having surgery. The main questions are: 1. Do psychosocial factors such as concerns about pain, sleep, anxiety affect the effectiveness of regional anesthesia? 2. Do psychosocial factors and regional anesthesia affect the amount of opioids used after surgery? 3. Do psychosocial factors and regional anesthesia affect development of chronic postsurgical pain?

Key facts

Study ID

NCT06466941

Run by

Brigham and Women's Hospital

People needed

1000

Starts

2024-07-03

Expected to finish

2028-12-31

Last updated by the study team

2026-05-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18
• English speaking
• Surgical or procedural patient who will be admitted postoperatively
• Willingness to answer psychosocial survey and/or audio recorded semi-structured interview

You may not qualify if…

• Cognitive dysfunction that precludes communication

Where it is running

• Brigham and Women's Hospital — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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