Changes in Attentional Control After a Focal Seizure.
Recruiting now
Conditions studied: Temporal Lobe Epilepsy, Frontal Lobe Epilepsy, Others Subtypes
In brief
Epilepsy is frequently associated with cognitive and attentional disorders. Several studies have pointed out that there are modifications of brain activity in resting state during peri-ictal period in EEG and functional MRI. However, to date, no study has assessed the changes in attentional control after a seizure. The investigators hypothesize that a localized discharge is associated with a disorganization of the networks engaged in attentional control. In this regard, the investigators propose a prospective longitudinal study assessing the changes in attentional control after a focal seizure.
Key facts
- Study ID
- NCT06466681
- Run by
- University Hospital, Lille
- People needed
- 100
- Starts
- 2024-03-04
- Expected to finish
- 2027-03-09
- Last updated by the study team
- 2026-04-27
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age superior to 18 and under 80
- Focal epilepsy with indication to pre-surgery work-up and 5 days programmed hospitalization dedicated to this work-up
- Normal global cognitive performance (standard progressive Raven matrices score > 5th percentile)
- Be affiliated to the social security system
- Have signed an informed consent
You may not qualify if…
- Pregnancy or breastfeeding
- Not able to give consent (Article 1121-8 of the CSP)
- Vulnerable person
- Being deprived of liberty by judicial or administrative decision (Article L 1121-6 of the CSP)
- Guardianship
- Have a high probability of not respecting the protocol or of abandoning the study
- Absence of any epileptic seizure recorded during the hospitalization
- Recurrent seizures preventing the recording of at least 24 hours without any seizure following a seizure.
Where it is running
- University Hospital, — Lille, France (enrolling)
Full record on ClinicalTrials.gov
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