Evaluation of the Efficacy of Compression With Tight Surgical Gloves in Patients With Taxane-based Therapy

Recruiting now · Not applicable

Conditions studied: Taxane-induced Peripheral Neuropathy

In brief

In this study, the effect of compression therapy of the hands with tight surgical gloves to reduce peripheral neuropathy in adult patients during the application of taxanes will be evaluated.

Key facts

Study ID

NCT06464536

Run by

St.Gallen University of Applied Sciences

People needed

114

Starts

2025-02-03

Expected to finish

2026-03-01

Last updated by the study team

2025-05-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Mamma or Urogenital carcinoma
• first treatment with Taxanes (nab-Paclitaxel, Paclitaxel, Docetaxel)
• signed informed consent
• sufficient proficiency in German or English

You may not qualify if…

• other therapy that could have caused peripheral neuropathy within the last 24 months (Taxane, Platin, Vincaalkaloids, etc.)
• History of neuropathy such as Raynaud's phenomenon, fibromyalgia and diabetic polyneuropathy
• Use of polyneuropathy medications including duloxetine; gabapentin/pregabalin; topical amitriptyline, ketamine, baclofen; oral cannabinoids; tricyclic antidepressants; and ganglioside monosialic acid
• such impaired cognition that prevents participation in the study according to the assessment of the caregivers

Where it is running

• University Hospital Zuerich — Zurich, Switzerland (enrolling)

Full record on ClinicalTrials.gov

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