Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas
Withdrawn before enrolling · Phase 1
Conditions studied: Glioblastoma, Brain Tumor
In brief
Magnetic resonance imaging, MRI, is a procedure that uses radio waves, a powerful magnet, and a computer to make a series of detailed pictures of areas inside the body. The goal of this study is to determine if MR fingerprinting, new way of acquiring MRI images, can help identify the extent of tumor spread in the brain, better than routine MRI images.
Key facts
- Study ID
- NCT06455189
- Run by
- Case Comprehensive Cancer Center
- People needed
- 0
- Starts
- 2025-12-01
- Expected to finish
- 2029-12-31
- Last updated by the study team
- 2026-07-01
Who can join
Age: 19 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age > 18
- MR imaging findings suggestive of GB
- Maximal tumor diameter greater than 3 cm
- Ability to provide written informed consent
- Ability to undergo MRI scan
- Consideration for biopsy, subtotal or gross total resection.
You may not qualify if…
- Contraindications to MRI
- Contraindication to surgical treatment
- Prior treatment for glioblastoma
- Stage II:
- Inclusion Criteria:
- Age > 18
- MR imaging findings suggestive of GB
- Maximal tumor diameter greater than 3 cm
- Ability to provide written informed consent
- Ability to undergo MRI scan
- Lesions amenable to gross total resection
- Presence of peritumoral FLAIR signal abnormality beyond the area of enhancement.
- Exclusion Criteria:
- Inability to undergo MRI imaging
- Participants undergoing only stereotactic biopsy or less than gross total resection
- Participants undergoing LITT
- Inability to consent for the study
- Previously treated/ recurrent glioma.
Where it is running
- University Hospitals Cleveland Medical Center, UH Department of Radiology, Case Comprehensive Cancer Center — Cleveland, Ohio, United States
Full record on ClinicalTrials.gov
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