Lidocaine Versus Bupivacaine in Orthognathic Surgery
Completed · Phase 4
Conditions studied: Pain, Postoperative, Numbness, Temperature Sensation, Perception of Touch
In brief
In this research study, we want to learn more about the impact of two different local anesthetics (bupivacaine and lidocaine) on patient experience following orthognathic (jaw) surgery. Both anesthetics are within the standard of care for dental and orthognathic procedures, but can vary in how quickly they take action and how long they last. This study will provide us with a greater understanding of how anesthetic choice affect patient outcomes, and how we can strive to make these outcomes as favorable as possible.
Key facts
- Study ID
- NCT06450028
- Run by
- Boston Children's Hospital
- People needed
- 64
- Starts
- 2024-10-01
- Expected to finish
- 2025-11-30
- Last updated by the study team
- 2026-08-04
Who can join
Age: 15 and older, up to 35. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Undergoing an orthognathic procedure at Boston Children's Hospital
- Between the ages of 15 and 35 years old
You may not qualify if…
- Any patient undergoing any other procedures in addition to their orthognathic procedure during the same sedation period (extraction, bone graft, etc.).
- Any patient with a history of chronic pain.
- Any patient with a history of an allergic reaction to bupivacaine or lidocaine.
- Any patient with known neurologic changes to the lip or chin.
- Any patient not enrolled in an Enhanced Recovery After Surgery (ERAS) Protocol.
- Any patient known to be pregnant or with a positive pregnancy test prior to the procedure.
Where it is running
- Boston Children's Hospital — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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