Examining the Role of Pain in the Link Between Early Childhood Adversity and Psychopathology

Completed · Not applicable

Conditions studied: Child Development

In brief

The goal of this study is to investigate the role of physical pain in the link between childhood adversity and later psychopathology. Children who are participating in a larger longitudinal study will be asked to submerge their hand in cold water and hold it in the cold water as long as possible. Participants will do this twice, once alone and once holding the hand of their parent, to examine the role of parental support in pain development. The study will examine self-report of pain and salivary cortisol response to pain. It is hypothesized that children who have been exposed to more adversity will experience increased pain response and increased psychopathology symptoms. It is expected that higher social support in the family will decrease this relationship.

Key facts

Study ID

NCT06445712

Run by

Washington University School of Medicine

People needed

39

Starts

2024-05-01

Expected to finish

2025-03-23

Last updated by the study team

2026-01-27

Who can join

Age: 6 and older, up to 9. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects who have been enrolled in our ongoing CARE study

You may not qualify if…

• Subjects who have not participated in the CARE study

Where it is running

• Laboratory for Child Brain Development — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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