The Feasibility of a Radiological Score Based on CT Signs for Recognizing Salvageable Bowel in Acute Mesenteric Ischemia
Recruiting now
Conditions studied: Acute Mesenteric Ischemia
In brief
Computed tomography (CT) is the standard modality for scanning patients with critical acute abdominal conditions, including suspected acute mesenteric ischemia (AMI). CT imaging can potentially differentiate between reversible and irreversible ischaemic damage of the bowel. This moment is pivotal in selecting the treatment strategy for AMI - in the absence of irreversible damage; reperfusion therapy can preserve intestinal viability, thereby avoiding the need for bowel resection. The present study tests the hypothesis that combining several symptoms may enhance the diagnostic performance of CT scanning in detecting salvageable bowel in patients with AMI. This study is an ancillary component of the AMESI study (Clinical Trials: NCT05218863) - a prospective, multicentre observational study aimed at identifying the incidence and describing the outcomes of acute mesenteric ischemia (AMI) in adult hospitalized patients. The ultimate purpose of the present study is to create a computed tomography-based radiological score for the assessment of bowel viability in patients with AMI.
Key facts
- Study ID
- NCT06445660
- Run by
- University of Tartu
- People needed
- 200
- Starts
- 2022-06-06
- Expected to finish
- 2025-05-31
- Last updated by the study team
- 2025-03-25
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Participant in AMESI study
- confirmed or suspected acute mesenteric ischaemia
- CT scan of the entire abdominal cavity / full body using intravenous contrast media is available
You may not qualify if…
- Scans without the use of an intravenous contrast media or those covering only a partial area of the abdomen will be excluded.
Where it is running
- Tartu University Hospital — Tartu, Estonia (enrolling)
Full record on ClinicalTrials.gov
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