Diagnostic Accuracy of EBV C Promoter Methylation Kit in Nasopharyngeal Carcinoma
Recruiting now
Conditions studied: Nasopharyngeal Carcinoma
In brief
This clinical study aims to evaluate the diagnostic performance of a new Epstein-Barr virus (EBV) C promoter methylation detection kit. All participants will undergo a series of diagnostic tests including VCA-IgA, EBNA1-IgA, and EBV-DNA assays. Additionally, nasopharyngeal swabs will be analyzed for EBV C promoter methylation. Confirmatory biopsy will be performed on all patients to establish a definitive diagnosis. This comprehensive approach seeks to assess the effectiveness of the methylation detection kit in a clinical setting.
Key facts
- Study ID
- NCT06445088
- Run by
- Sun Yat-sen University
- People needed
- 908
- Starts
- 2024-05-29
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2024-06-25
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Participants who meet the following Article 1 and also meet one of Articles 2 to 6 can be enrolled:
- Understand, sign, and date the informed consent document to participate in the study
- Display one or more symptoms or signs indicative of nasopharyngeal carcinoma
- Test positive for EBV antibodies or EBV DNA
- Be diagnosed with other head and neck carcinomas
- Be diagnosed with malignancies associated with EBV infection
- Require differential diagnosis from nasopharyngeal carcinoma during endoscopic or other imaging examinations
- Fulfill any additional conditions deemed appropriate by the investigator for inclusion in this study
You may not qualify if…
- Have been diagnosed with nasopharyngeal carcinoma and have undergone treatment
- Experience relapse or metastasis of nasopharyngeal carcinoma following treatment
- Have unsuccessful nasopharyngeal swab collections
- Present any other conditions considered by the investigator as unsuitable for participation in this trial
Where it is running
- Fujian Cancer Hospital — Fuzhou, Fujian, China (enrolling)
- Sun Yat-Sen University Cancer Center — Guangzhou, Guangdong, China (enrolling)
- ZhongShan City People's Hospital — Zhongshan, Guangdong, China (enrolling)
- The First Affiliated Hospital of Guangxi Medical University — Nanning, Guangxi, China (enrolling)
- Wuzhou Red Cross Hospital — Wuzhou, Guangxi, China (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.