Barts Endocarditis Research Registry

Recruiting now

Conditions studied: Infective Endocarditis, Endocarditis, Endocarditis, Bacterial

In brief

The Barts Endocarditis Research Registry is being set up to give a unique opportunity to assess the characteristics of Infective Endocarditis (IE) in our population cohort, the current use of imaging techniques, as well as the implementation of the ESC guidelines and its consequence in terms of prognosis. All this will help improve the diagnosis and management of IE. The registry will also form the core of all our subsequent work, including interventional studies. The endocarditis research registry is to record the epidemiological, demographic, microbiological, surgical and outcome data in our cohort of endocarditis patients. This work will underpin all future work in endocarditis by clearly defining our patient cohort and the outcomes from treatment. We have a series of studies planned that we believe will influence the management of endocarditis (we are working up proposals for genomic and therapeutic trials that will subsequently be presented for ethical and hospital approval). The registry will be generic to all our planned studies, and will allow us to capture data to assess treatment effectiveness

Key facts

Study ID

NCT06434012

Run by

Queen Mary University of London

People needed

1000

Starts

2019-04-24

Expected to finish

2029-04-30

Last updated by the study team

2026-07-17

Who can join

Age: 16 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• • Patients aged 16 and over (Patients under 16 years of age are not admitted to Barts Heart Centre)
• Patients admitted to Barts Heart Centre with confirmed Endocarditis (see above)
• Patients attending outpatients with confirmed/suspected Endocarditis
• Patients with possible IE who complete treatment for endocarditis
• Patients with cardiac device related Endocarditis
• Patients with the ability to provide informed consent

You may not qualify if…

• • Patients with pacemaker pocket infection with no evidence of pacemaker lead or valve infection
• Patients who refuse consent to be included in the research database
• Patients with "rejected" endocarditis

Where it is running

• St Bartholomews Hospital — London, United Kingdom (enrolling)

Full record on ClinicalTrials.gov

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