Comparative Evaluation of Indirect vs. Direct Pulp Capping in Deep Carious Mandibular Molars

Recruiting now · Not applicable

Conditions studied: Indirect Pulp Capping, Reversible Pulpitis

In brief

Aim: To compare the outcome of indirect and direct pulp capping after partial or complete caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis. Objectives: 1. To evaluate the clinical and radiographic success of indirect pulp capping after partial caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis. 2. To evaluate the clinical and radiographic success of direct pulp capping after complete caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis. 3. To evaluate pain incidence and severity after indirect and direct pulp capping after partial and complete caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis.

Key facts

Study ID

NCT06433297

Run by

Postgraduate Institute of Dental Sciences Rohtak

People needed

106

Starts

2024-05-23

Expected to finish

2026-03-23

Last updated by the study team

2026-02-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• The patient should be ≥18 years of age.
• Restorable mature permanent 1st and 2nd Mandibular molars with deep caries (reaching inner quarter of dentine)
• Tooth should give positive response to pulp sensibility testing.
• Clinical diagnosis of moderate pulpitis.
• Radiographic finding of periapical index (PAI) score ≤2.
• Healthy periodontium (probing pocket depth ≤3 mm and mobility within normal limit).
• Pulp exposure after complete caries excavation.
• No pulp exposure after incomplete caries excavation

You may not qualify if…

• Teeth with immature roots.
• Pulp exposure after incomplete caries excavation.
• No pulp exposure after complete caries excavation.
• Bleeding could not be controlled in 5 minutes.
• Signs of pulpal necrosis, sinus tract, swelling, insufficient bleeding after pulp exposure.
• History of analgesic intake in previous 1 week, or antibiotic intake in 1 month.
• Internal/external resorption.
• Contributory medical history (alcoholism, smokers, diabetic, hypertension, drug dependency, Heart or valve disease, hepatitis, herpes, immunodeficiency (HIV), infectious diseases, kidney or liver, migraine)

Where it is running

• PGIDS, Rohtak — Rohtak, Haryana, India (enrolling)

Full record on ClinicalTrials.gov

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