The Electronic Cardiovascular Genetics (eCG) Clinic for Presymptomatic Genetic Counselling
Recruiting now · Not applicable
Conditions studied: Inherited Cardiac Disease
In brief
Inherited cardiovascular conditions generally inherit following an autosomal dominant pattern. When a mutation is detected in the proband, relatives can have predictive DNA testing, and - when they are carrier - be monitored and timely treated if needed. Currently, less than half of relatives attends genetic counselling. With the eCG Family Clinic, an easily accessible virtual clinic which better suits the needs and preferences of relatives will be offered. At the eCG Family Clinic, relatives will receive tailored information to support informed decision-making, a DNA-test at home if desired, and can be referred for local cardiac monitoring if relatives appear to be a carrier. Implementation of the eCG Family Clinic in clinical practice is compared to current practice in this clinical trial.
Key facts
- Study ID
- NCT06431425
- Run by
- UMC Utrecht
- People needed
- 170
- Starts
- 2023-11-15
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2025-09-17
Who can join
Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Probands:
- > 18 y/o
- Diagnosed with inherited hypertrophic cardiomyopathy (HCM) or dialted cardiomyopathy (DCM))
- Class 4 or 5 variant identified.
- Access to a working laptop or computer device.
- At risk relatives:
- > 18 y/o
- First degree family member, or second degree in case of a deceased first degree relative
- Access to a working laptop or computer device.
- Healthcare professionals:
- Genetic counsellors of the genetics department directly involved in the care given to the family.
You may not qualify if…
- Insufficient control of the Dutch language or digital skills.
Where it is running
- University Medical Centre Utrecht — Utrecht, Utrecht, Netherlands (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.