Exercise Prehabilitation for Locoregional Esophageal Cancer

Recruiting now · Not applicable

Conditions studied: Esophageal Cancer

In brief

The purpose of the study is to examine the feasibility and acceptability of exercise "prehabilitation" for patients preparing for esophageal cancer resection (removal).

Key facts

Study ID

NCT06430346

Run by

H. Lee Moffitt Cancer Center and Research Institute

People needed

20

Starts

2024-05-21

Expected to finish

2027-05-01

Last updated by the study team

2025-12-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Biopsy-proven locoregional esophageal cancer (LEC)
• Eastern Cooperative Oncology Group (ECOG) performance status 0-2
• Treatment plan including neoadjuvant chemoradiation therapy and surgical resection
• Ability to read and speak English

You may not qualify if…

• Regular engagement in resistance training (2x/week targeting all major muscle groups)
• Screen failure for exercise safety based on PAR-Q
• Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease
• Recent fracture or acute musculoskeletal injury that precludes ability to participate in resistance training safely
• Numeric pain rating scale of 7 or more out of 10
• Myopathic or rheumatologic disease that impacts physical function

Where it is running

• Moffitt Cancer Center — Tampa, Florida, United States (enrolling)

Full record on ClinicalTrials.gov

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