Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas
Recruiting now · Not applicable
Conditions studied: Empyema, Pleural, Pleural Infection
In brief
Infections of the pleural space are common, and patients require antibiotics and chest drain placement to evacuate the chest from the infected fluid. Chest drains can get blocked by the drainage fluid and material. For this reason, it is thought that flushing the chest drain with saline solution, can help maintain the patency of the tube. This proposed study will evaluate the impact of regular chest drain flushing on the length of time to chest tube removal and total hospitalization as well as improvement in chest imaging and the need for additional interventions on the infected space.
Key facts
- Study ID
- NCT06427538
- Run by
- Vanderbilt University Medical Center
- People needed
- 96
- Starts
- 2024-06-21
- Expected to finish
- 2026-12-30
- Last updated by the study team
- 2026-02-20
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with complicated parapneumonic pleural effusion and empyema requiring chest tube placement as standard of care for inpatient management of their pleural space infection with or without intrapleural tissue plasminogen activator and deoxyribonuclease therapy
- Age > 18 years old.
You may not qualify if…
- Patients who have surgical tubes that can't accommodate a three-way stopcock.
- Study subject has any disease or condition that interferes with the safe completion of the study.
- Inability to provide informed consent.
- Inability to undergo a chest X-ray.
- If the managing clinician believes the chest tube will be placed for less than 24 hours.
- Patients with an indwelling pleural catheter (IPC)
Where it is running
- Henry Ford — Sterling Heights, Michigan, United States (enrolling)
- Creighton University — Omaha, Nebraska, United States (enrolling)
- Mount Sinai — New York, New York, United States (enrolling)
- Vanderbilt University Medical Center — Nashville, Tennessee, United States (enrolling)
- Virginia Commonwealth University — Richmond, Virginia, United States (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.