Central-boost Ablative Radiation Therapy for Solid Tumors (CBART)
Recruiting now · Phase 2
Conditions studied: Pancreatic Cancer
In brief
In the case of large tumors or tumors closely adjacent to organs at risk, ablative doses offered by stereotactic body radiation therapy (SBRT) could not be delivered. Therefore, a technique that could provide high radiation doses to tumors without increasing of risks of severe adverse effects is required.
Key facts
- Study ID
- NCT06427460
- Run by
- Changhai Hospital
- People needed
- 67
- Starts
- 2024-05-12
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2024-05-23
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Aged 18-75 years.
- Pathologically confirmed lung, liver, pancreas or retroperitoneal malignant tumor.
- Oligometastasis in the case of metastatic tumor
- the shortest diameter ≥2cm or the distance from the tumor to the organs at risk less than 5mm
- ECOG of 0 to 1 point
- No abnormality in blood routine test, liver and kidney function test and coagulation test (White blood cell count ≥4.0×10\^9/L, neutrophil count ≥2.0×10\^9, hemoglobin level ≥100g/L, platelet count ≥100×10\^9/L, ALT and AST level < 2.5 times the upper limit of normal, total bilirubin and creatinine level within the normal, international normalized ratio <2)
You may not qualify if…
- History of radiotherapy for the lesion
- History of tumor within 5 years
- ECOG ≥2 points
- Significant abnormality in blood routine test, liver and kidney function test and coagulation test
- Active inflammatory bowel disease in the case of pancreas or retroperitoneal tumor
- Gastrointestinal bleeding or perforation within 6 months in the case of pancreas or retroperitoneal tumor
- Infections required antibiotics
- Heart or respiratory insufficiency
- Pregnant or breastfeeding women
Where it is running
- Huojun Zhang — Shanghai, Shanghai Municipality, China (enrolling)
Full record on ClinicalTrials.gov
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