Routinely Collected Clinical Data and Evaluation of Antimicrobial Target Attainment
Recruiting now
Conditions studied: Infections, Bacterial, Pharmacokinetics, Drug Monitoring, Drug-Related Side Effects and Adverse Reactions
In brief
The primary aim of the study is to determine the proportion of individuals receiving beta-lactam antibiotics at Imperial College Healthcare NHS Trust in whom drug concentration targets are achieved.
Key facts
- Study ID
- NCT06427317
- Run by
- Imperial College London
- People needed
- 323
- Starts
- 2024-03-19
- Expected to finish
- 2027-03-19
- Last updated by the study team
- 2024-05-23
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 18 years of age or above.
- Under follow-up for management of infection at Imperial College NHS Trust
- Received a beta-lactam antibiotic within the last 48 hours (or are planned to start imminently).
- Provides informed written consent see below, or lacks capacity to provide consent because of one of the following conditions (and declaration provided by personal consultee):
- Delirium which may be caused or exacerbated by having an infection.
- Suspected/confirmed central nervous system infection.
- Critical illness requiring sedation and/or intubation and ventilation which is caused by or exacerbated by having an infection.
You may not qualify if…
- Less than 18 years of age
- Severe anaemia (Hb < 70g/l)
- Platelets < 50x10\^9/l, INR >1.5 or other known blood clotting impairment
- Patient with terminal diagnosis receiving palliative care input who may experience distress if approached for this study.
- Enrolled in a clinical trial which stipulates exclusion from other studies including observational studies.
- Patients with restricted liberty, prisoners or under legal protection.
Where it is running
- Imperial College Healthcare NHS Trust — London, United Kingdom (enrolling)
Full record on ClinicalTrials.gov
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