Cardiac Amyloidosis pRevaleNce of in OLDer Subjects Affected by Heart Failure

Recruiting now

Conditions studied: Cardiac Amyloidosis

In brief

Tne aim purpose of this observational, multicentre and propective study is to determine the prevalence of cardiac amyloidosis in geriatric patients aged 80 years and older hospitalized within the last 12 months for heart failure with left ventricular hypertrophy (septum ≥ 12 mm) on echocardiography

Key facts

Study ID

NCT06427304

Run by

Gérond'if

People needed

637

Starts

2024-07-01

Expected to finish

2028-02-02

Last updated by the study team

2026-04-20

Who can join

Age: 80 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Aged ≥ 80 years
• Hospitalised for decompensation of heart failure in the last 12 months
• Subjects with hypertrophy of the septum or left ventricle at cardiac echography (defined as ≥ 12 mm)
• Subjects able to undergo a bone scintigraphy scan
• Subjects willing to participate

You may not qualify if…

• Subjects refusing to participate
• Subjects admitted to palliative care unit.
• Subjects under guardianship
• Subjects with a definite diagnosis of cardiac amyloidosis

Where it is running

• Bretonneau Hospital — Paris, Île-de-France Region, France (enrolling)
• CHU Nantes — Nantes, Loire-Atlantique, France (enrolling)
• CHU Poitiers — Poitiers, New Aquitaine, France (enrolling)
• CHU Rouen, Charles Nicole hospital — Rouen, Normandy, France (enrolling)
• CHU Montpellier — Montpellier, Occitanie, France (enrolling)
• CHU Toulouse — Toulouse, Occitanie, France (enrolling)
• CHU Amiens Picardie — Amiens, France (enrolling)
• CHU Angers — Angers, France (enrolling)
• CHU Bordeaux — Bordeaux, France (enrolling)
• Centre Hospitalier de Carcassonne — Carcassonne, France (enrolling)
• Centre Hospitalier Intercommunal de Castres-Mazamet — Castres, France (enrolling)
• CHU Trousseau-Tours — Chambray-lès-Tours, France (enrolling)
• CHU Dijon — Dijon, France (enrolling)
• CHU Grenoble Alpes — Grenoble, France (enrolling)
• CHU Lille — Lille, France (enrolling)
• CHU Limoges — Limoges, France (enrolling)
• CHU Lyon — Lyon, France (enrolling)
• CHU Marseille — Marseille, France (enrolling)
• Clinique du Millénaire-Montpellier — Montpellier, France (enrolling)
• CHRU Nancy — Nancy, France (enrolling)
• CHU Nice — Nice, France (enrolling)
• Hôpital Privé Gériatrique LES SOURCES-Nice — Nice, France (enrolling)
• CHU Orléans — Orléans, France (enrolling)
• CHU Rennes — Rennes, France (enrolling)
• CHRU Tours-Bretonneau Hospital — Tours, France (enrolling)

Full record on ClinicalTrials.gov

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