Self-reported and Experimental Pain in Patients Undergoing Orthodontic Treatment

Completed

Conditions studied: Pain

In brief

Pressure Pain Threshold (PPT) is defined as the minimum force applied to an area that is perceived as pain. PPT is considered an objective measurement tool to assess pain levels. Studies have assessed the difference in pain levels between clear aligners and fixed appliances using subjective pain scales. No study has utilized PPT to evaluate the difference in pain between aligners and fixed braces at different time points. This study will aim to compare the self- reported and experimental pain perception between the clear aligner and fixed appliance therapies during the phase of crown alignment and to assess how long pain is perceived in the following five days from the adjustment of the appliance.

Key facts

Study ID

NCT06426238

Run by

Midwestern University

People needed

38

Starts

2024-01-03

Expected to finish

2025-06-01

Last updated by the study team

2025-06-08

Who can join

Age: 14 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• consecutive consented patients (> 14 years old) beginning an orthodontic treatment on both arches, either with aligners or fixed appliance at the Midwestern University, Multidisciplinary Clinic;
• patients in possession of an email address and Internet connection.

You may not qualify if…

• patients with generalized systemic conditions known to affect the overall body pain and pressure pain threshold assessment (e.g., fibromyalgia, autoimmune conditions such as multiple sclerosis, rheumatoid arthritis),
• untreated dental caries.

Where it is running

• Midwestern University — Downers Grove, Illinois, United States

Full record on ClinicalTrials.gov

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