Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)
Recruiting now
Conditions studied: Pediatric Cancer
In brief
To evaluate the ability of a multidisciplinary and multisite group, the Pediatric Evolutionary Tumor Board (pedsETB), to develop additional therapeutic strategies in patients without curative options or with suboptimal outcomes.
Key facts
- Study ID
- NCT06423950
- Run by
- H. Lee Moffitt Cancer Center and Research Institute
- People needed
- 35
- Starts
- 2024-05-01
- Expected to finish
- 2027-04-01
- Last updated by the study team
- 2026-02-09
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Participant must be considered likely incurable given the standard of care. This is inclusive of patients newly diagnosed, relapsed or in remission but at high risk of recurrence, with suboptimal responses to previous therapy, or with many potentially beneficial, but unlikely curative options for care.
- The site investigator will make this determination based on their experience.
- Participant must have an age-appropriate performance status: Karnofsky 50 or more for patients 16 years of age or older OR Lansky score of 50 or more for patients less than16 years of age.
- Participant and/or parents or legal guardian and primary oncologist must be willing to consider the therapeutic strategies recommended by the pedsETB.
- Participant must be willing to be followed over time and allow collection of clinical data including scans, available blood and lab samples, and optional pedsETB serial blood sampling.
- All Participants and/or their parents or legal guardians must have the ability to understand and the willingness to sign a written informed consent or assent document.
You may not qualify if…
- Participants without known therapies to reliably induce a response are excluded from pedsETB and should seek clinical trials.
Where it is running
- Moffitt Cancer Center — Tampa, Florida, United States (enrolling)
Full record on ClinicalTrials.gov
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