A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
Recruiting now · Phase 1/Phase 2
Conditions studied: Epilepsy, Temporal Lobe
In brief
This is a multicenter, single arm, open label clinical trial that is designed to test the safety and preliminary efficacy of single administration inhibitory nerve cells called interneurons (NRTX-1001), into both temporal lobes of subjects with drug-resistant bilateral mesial temporal lobe epilepsy.
Key facts
- Study ID
- NCT06422923
- Run by
- Neurona Therapeutics
- People needed
- 10
- Starts
- 2024-11-14
- Expected to finish
- 2042-06-15
- Last updated by the study team
- 2026-01-07
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Medical College of Wisconsin — Milwaukee, Wisconsin, United States (enrolling)
- University of Southern California Keck Hospital — Los Angeles, California, United States (enrolling)
- UC Irvine Medical Center — Orange, California, United States (enrolling)
- Stanford University — Palo Alto, California, United States (enrolling)
- University of California San Diego — San Diego, California, United States (enrolling)
- University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States (enrolling)
- University of Colorado Anschutz Medical Campus — Aurora, Colorado, United States (enrolling)
- University of Chicago — Chicago, Illinois, United States (enrolling)
- University of Iowa Health Care — Iowa City, Iowa, United States (enrolling)
- SUNY Upstate Medical University — Syracuse, New York, United States (enrolling)
- Atrium Health — Charlotte, North Carolina, United States (enrolling)
- Duke University Hospital — Durham, North Carolina, United States (enrolling)
- Wake Forest Baptist Medical Center — Winston-Salem, North Carolina, United States (enrolling)
- Oregon Health and Science University — Portland, Oregon, United States (enrolling)
- UTHealth Houston — Houston, Texas, United States (enrolling)
- UVA Health University Medical Center — Charlottesville, Virginia, United States (enrolling)
- University of California San Francisco — San Francisco, California, United States
Full record on ClinicalTrials.gov
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