Epidemiological Investigation of Helicobacter Pylori-infected Patients and the Effect of Eradication Treatment on Dyspepsia Symptoms

Recruiting now

Conditions studied: Helicobacter Pylori Infection, Dyspepsia

In brief

The objectives of this multicenter, prospective, observational study were to investigate the incidence of dyspeptic symptoms in patients with Helicobacter pylori (H. pylori) infection and to continuously follow up the remission of dyspeptic symptoms after H. pylori eradication, so as to provide reference for the clinical diagnosis and treatment strategies of patients with H. pylori infection and dyspeptic symptoms.

Key facts

Study ID

NCT06422052

Run by

Shanghai Jiao Tong University School of Medicine

People needed

2242

Starts

2024-03-11

Expected to finish

2025-05-31

Last updated by the study team

2024-12-30

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female patients aged 18-80 years
• H. pylori infection diagnosed by 13C/ 14C-UBT (> 2 times the cutoff value) and/or gastroscopy (rapid urease strong positive and histological positive)
• Treatment-naive patients with Helicobacter pylori
• Ability and willingness to participate in the study and to sign and give informed consent

You may not qualify if…

• Under 18 or over 80 years old
• Organic digestive diseases, such as active peptic ulcer, gastroesophageal reflux, gastrointestinal bleeding, acute/chronic pancreatitis, acute/chronic cholecystitis, gallstones, intestinal obstruction, inflammatory bowel disease, etc.
• Combined with melena, hematemesis, anemia, emaciation and other alarm symptoms
• Pregnant and lactating women
• History of cancer
• History of subtotal gastrectomy
• Severe organ dysfunction of heart, liver, kidney, lung and other important organs and congenital diseases, such as grade IV heart failure, liver failure, uremia, respiratory failure, hemophilia, Wilson's disease, etc.

Where it is running

• Chongqing Daping Hospital — Chongqing, Chongqing Municipality, China (enrolling)
• The Ninth People's Hospital of Chongqing — Chongqing, Chongqing Municipality, China (enrolling)
• The People's Hospital of Kaizhou District, CQ — Chongqing, Chongqing Municipality, China (enrolling)
• The First Affiliated Hospital of Xiamen University — Xiamen, Fujian, China (enrolling)
• The People's Hospital of Wuwei — Wuwei, Gansu, China (enrolling)
• The First People's Hospital of Qinzhou — Qinzhou, Guangxi, China (enrolling)
• The First Affiliated Hospital of Henan University of Science and Technology — Luoyang, Henan, China (enrolling)
• Yongcheng People's Hospital of Henan Province — Shangqiu, Henan, China (enrolling)
• Xuchang Central Hospital — Xuchang, Henan, China (enrolling)
• Union Hospital, Tongji Medical College, Huazhong University of Science and Technology — Wuhan, Hubei, China (enrolling)
• Baotou Central Hospital — Baotou, Inner Mongolia, China (enrolling)
• Dalian Friendship Hospital — Dalian, Liaoning, China (enrolling)
• The First Affiliated Hospital of Dalian Medical University — Dalian, Liaoning, China (enrolling)
• Renji Hospital, School of Medicine, Shanghai Jiao Tong University — Shanghai, Shanghai Municipality, China (enrolling)
• Ruijin Hospital Luwan Branch — Shanghai, Shanghai Municipality, China (enrolling)
• Shanghai Construction Group Hospital — Shanghai, Shanghai Municipality, China (enrolling)
• Shanghai East Hospital — Shanghai, Shanghai Municipality, China (enrolling)
• Shanghai Putuo Liqun Hospital — Shanghai, Shanghai Municipality, China (enrolling)
• Shanghai Songjiang Central Hospital — Shanghai, Shanghai Municipality, China (enrolling)
• West China Fourth Hospital, Sichuan University — Chengdu, Sichuan, China (enrolling)
• First Teaching Hospital of Tianjin University of Traditional Chinese Medicine — Tianjing, Tianjing, China (enrolling)
• The Second People's Hospital of Kashgar, Xinjiang — Kashgar, Xinjiang, China (enrolling)
• Second People's Hospital of Jinning District, Kunming City — Kunming, Yunnan, China (enrolling)
• Ningbo Hangzhou Bay Hospital — Ningbo, Zhejiang, China (enrolling)
• The People's Hospital of Shengzhou — Ningbo, Zhejiang, China (enrolling)

Full record on ClinicalTrials.gov

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