An Observational Study to Assess Real-World Use of Upadacitinib Tablets in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis in China

Recruiting now

Conditions studied: Atopic Dermatitis

In brief

Atopic dermatitis (AD) is a skin condition that may cause a rash and itching due to inflammation of the skin. Upadacitinib is an approved drug for treating AD. Approximately 1000 adolescents and adult participants who are prescribed upadacitinib by their physician in accordance with local label will be enrolled in up to 40 sites in China. Participants will receive oral upadacitinib tablets as prescribed by their physician according to their routine clinical practice and local label. Participants will be followed up for approximately 12 months. There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.

Key facts

Study ID

NCT06421740

Run by

AbbVie

People needed

1000

Starts

2024-06-07

Expected to finish

2026-06-01

Last updated by the study team

2026-05-13

Who can join

Age: 12 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adolescents (body weight >= 40 kg at the Baseline Visit for patients between >= 12 and < 18 years of age) and adults at the time of enrollment.
• Clinical diagnosis of moderate to severe atopic dermatitis at the time of enrollment.
• UPA treatment is indicated for AD and prescribed as per Chinese label / SmPC.
• The decision to prescribe UPA is made prior to and independent of study participation.
• The participant should not be treated with UPA prior to this study.
• Participants who are willing and able to participate in the collection of patient-reported data, including ePROs and eDiary via apps.
• The participant (legal representative for adolescents) voluntarily signed an informed consent before any study-related activities are conducted.

You may not qualify if…

• The participant is currently participating in interventional research (not including noninterventional study, observational study, or registry participation).
• Any circumstances that the investigator believes may limit the patient's participation and compliance with study procedures.

Where it is running

• Sichuan Provincial People's Hospital /ID# 268314 — Chengdu, Sichuan, China (enrolling)
• China-Japan Friendship Hospital /ID# 274778 — Beijing, Beijing Municipality, China
• Peking University First Hospital /ID# 274865 — Beijing, Beijing Municipality, China
• Peking Unversity Third hospital /ID# 274864 — Beijing, Beijing Municipality, China
• Peking Union Medical College Hospital (East) - Dongdan Campus /ID# 264193 — Beijing, Beijing Municipality, China
• The First Affiliated Hospital Of Fujian Medical University /ID# 268210 — Fuzhou, Fujian, China
• Changgeng Hospital /ID# 268209 — Xiamen, Fujian, China
• Guangzhou Dermatology Hospital /ID# 271684 — Guangzhou, Guangdong, China
• The Fifth Affiliated Hospital Of Sun Yat-Sen University /ID# 268618 — Zhuhai, Guangdong, China
• Hainan Fifth People's Hospital /ID# 269747 — Hainan, Hainan, China
• Hebei Engineering University Affiliated Hospital /ID# 268660 — Handan, Hebei, China
• The Second Affiliated Hospital Of Harbin Medical University /ID# 270872 — Harbin, Heilongjiang, China
• People's Hospital of Henan Province /ID# 269744 — Zhengzhou, Henan, China
• Wuhan Integrated TCM & Western Medicine Hospital（Wuhan No.1 Hospital) /ID# 272374 — Wuhan, Hubei, China
• Tongji Hospital /ID# 269745 — Wuhan, Hubei, China
• Xiangya Hospital Central South University /ID# 272373 — Changsha, Hunan, China
• Nanjing Drum Tower Hospital /ID# 268616 — Nanjing, Jiangsu, China
• Affiliated Hospital Of Nantong University /ID# 269743 — Nantong, Jiangsu, China
• The First Affiliated Hospital of Soochow University /ID# 269742 — Suzhou, Jiangsu, China
• The Affiliated Hospital of Xuzhou Medical College /ID# 268208 — Xuzhou, Jiangsu, China
• Dalian Dermatosis Hospital /ID# 272495 — Dalian, Liaoning, China
• The People's Hospital of Liaoning Province /ID# 268206 — Shenyang, Liaoning, China
• Shandong Provincial Hospital /ID# 268661 — Jinan, Shandong, China
• Jining Medical University - Affiliated Hospital /ID# 270873 — Jining, Shandong, China
• Weifang People'S Hospital /ID# 268659 — Weifang, Shandong, China

Full record on ClinicalTrials.gov

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