QL vs LAI for Palatoplasty

Recruiting now · Not applicable

Conditions studied: Post-operative Pain, Opioid Use, Cleft Palate

In brief

This study will consist of patients ages 6-18 who are undergoing a surgery on the hard or soft palate of the mouth (palatoplasty), with removal of bone from the front of the hip (anterior iliac bone graft harvesting). The patients will be randomized to receive either a unilateral QL block by an anesthesiologist, or local anesthetic infiltration at the surgical incision by the surgeon. The primary aim will be assessing post-operative pain in the first 48 hours after surgery. Secondary outcomes will include pain medication use in the first 48 hours after surgery, block resolution time, and evaluating any complications associated with the QL block or local anesthetic infiltration.

Key facts

Study ID

NCT06420336

Run by

Medical University of South Carolina

People needed

46

Starts

2024-06-25

Expected to finish

2027-01-31

Last updated by the study team

2026-07-09

Who can join

Age: 6 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients undergoing palatoplasty with autologous bone graft from the anterior iliac crest.
• Ages 6-18 years of age
• Planned admission post-op
• ASA Status Range: 1-3

You may not qualify if…

• Contraindication to QL blocks or LAI which may include:
• overlying infection skin at the block needle insertion site
• coagulopathies
• known bleeding disorders
• Allergy to local anesthetic
• Cognitive or developmental impairment that would limit ability to report pain.
• Non-English Speaking/Writing
• Subjects or their parent/guardian unable or choose to not give informed consent/assent.

Where it is running

• Medical University of South Carolina — Charleston, South Carolina, United States (enrolling)

Full record on ClinicalTrials.gov

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