Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity

Recruiting now · Not applicable

Conditions studied: Pain, Acute

In brief

This interventional study aims to test gait biomechanics in healthy individuals with and without experimental muscle pain in the lower extremities. The study aims to: A) Examine how experimental muscle pain in different types of muscles (ankle plantar-flexion, knee extension, and flexion muscles) affects kinematics, kinetics, and muscle activation Participants will receive six muscle injections: a) Hypertonic saline (painful condition) and b) Isotonic saline (control condition) in 1) m. gastrocnemius, 2) m. semitendinosus, and 3) m. biceps femoris.

Key facts

Study ID

NCT06411197

Run by

Kristian Kjær Petersen

People needed

36

Starts

2023-11-08

Expected to finish

2026-12-31

Last updated by the study team

2025-10-02

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy men and women aged 18-45 years

You may not qualify if…

• Pregnancy
• Drug addiction, defined as the use of cannabis, opioids, or other drugs
• Previous or current neurologic or musculoskeletal illnesses
• Current pain
• Lack of ability to cooperate

Where it is running

• Aalborg University — Aalborg, North Denmark, Denmark (enrolling)

Full record on ClinicalTrials.gov

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