Evaluation of 3D Surface Scanning for Virtual-CT Based Radiation Therapy Treatment Planning

Completed

Conditions studied: Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm

In brief

This study evaluates if three dimensional (3D) surface images can be used instead of the standard computed tomography (CT) scans for treatment planning in electron radiation therapy. 3D scanning has previously been used by several groups to design patient-specific devices to be 3D printed, and as has shown excellent agreement with CT obtained surfaces. Using 3D surface imaging instead of x-ray based CT, benefits include: no ionizing radiation used to produce images, shorter time between patient consultation and treatment, and ability to produce and evaluate patient-specific devices for electron therapy earlier in the treatment planning process. This study may help researchers learn how 3D surface scanning may be used to produce a virtual CT image of patient surfaces, and accurately replace traditional planning CT for treatment planning of electron based radiation therapy.

Key facts

Study ID

NCT06409000

Run by

Mayo Clinic

People needed

26

Starts

2021-01-19

Expected to finish

2026-02-05

Last updated by the study team

2026-02-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults (18 years old or older)
• Capable of consent
• Receiving electron therapy and a planning CT scan
• Consent to two 3D surface scans of treatment area

You may not qualify if…

• Pediatric patients
• Mentally incapable of study consent
• Receiving electron radiation for a breast cancer boost
• Receiving electrons for total skin electron therapy
• Patients with epilepsy or other seizure disorders

Where it is running

• Mayo Clinic in Arizona — Scottsdale, Arizona, United States

Full record on ClinicalTrials.gov

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