Predicting Esophageal Cancer Borders Using PET-Imaging

Recruiting now · Phase 2

Conditions studied: Esophagus Cancer, Stage I, Esophagus Cancer, Stage II

In brief

The study examines the diagnostic precision of endosonography, mpMRI and PET/CT in defining tumor boundaries and tumor spread before and after neoadjuvant therapy and definitive surgery.

Key facts

Study ID

NCT06408116

Run by

University Hospital Heidelberg

People needed

30

Starts

2024-03-01

Expected to finish

2028-04-01

Last updated by the study team

2026-03-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Histologically confirmed adenocarcinoma or squamous cell carcinoma of the esophagus, including AEG I and AEG II tumors in the primary situation
• Planned surgical treatment of esophageal carcinoma
• Possible staging advantage through FAPI PET/CT diagnostics
• Patient information and written consent
• > KI 60% or ECOG 0/1 (at least: self-sufficiency)
• Age ≥ 18 years

You may not qualify if…

• Previous radiation therapy in the tumor region
• Previous tumor disease with < 5 years of remission
• Surgical therapy is not functionally or technically possible
• Distant metastasis
• Patient is not capable of giving consent
• Concurrent participation in another clinical trial that could affect the results of this trial or the other trial
• Illnesses that do not allow the person concerned to assess the nature and scope as well as possible consequences of the clinical study
• pregnant or breastfeeding women
• Signs that the person taking part is unlikely to comply with the therapy (e.g. unwillingness to cooperate)

Where it is running

• Department of Radiotherapy, University of Heidelberg — Heidelberg, Germany (enrolling)

Full record on ClinicalTrials.gov

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