Cervical Cancer Susceptible Population Classification

Recruiting now

Conditions studied: Cervical Cancer Susceptible Population Classification

In brief

Cervical cancer is the third most common lethal tumor globally, causing around a quarter million deaths annually, despite the availability of HPV vaccines. Recent Genome-wide association studies (GWAS) have identified numerous genetic markers linked to cervical cancer, including rs10175462, rs10007915, rs35721900, and rs61646675, which have been verified as being related to susceptibility to cervical cancer. However, many reports lack clarity, consistency, and validation. In this comprehensive study, we will analyze the genomic risk factors associated with cervical cancer, classify individuals into different risk categories, and explore potential biomarkers and therapeutics.

Key facts

Study ID

NCT06405945

Run by

Anhui Provincial Hospital

People needed

10000

Starts

2024-05-01

Expected to finish

2036-06-01

Last updated by the study team

2024-05-09

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Subjects aged >=18 years at time of consent
• Intended to undergo screening colposcopy
• Considered by a physician or healthcare provider as being of "average risk" for cervical cancer
• Willing to consent to blood draw cervical disease treatments
• Willing to sonsent to follow-up for five years as per protocol

You may not qualify if…

• History of cervical cancer
• History of any malignancy (patients who have undergone surgical removal of skin squamous cell cancer may be enrolled provided the procedure was completed at least 12 months prior to the date of provision of informed consent for the study)
• Currently taking any anti-neoplastic or disease-modifying anti-rheumatic drugs.
• Any major physical trauma (e.g. disruption of tissue, surgery, organ transplant, blood product transfusion) within the 30 days leading up to the provision of informed consent
• Known medical condition which, in the opinion of the investigator, should preclude enrollment into the study

Where it is running

• The First Affiliated Hospital of USTC — Hefei, Anhui, China (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.