Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Colorectal Cancer

In brief

This study is a further observation and follow-up of the patients enrolled in the registration number NCT05920980 to further evaluate the effect of long-term infusion of lidocaine on postoperative chronic pain, long-term quality of life and survival rate in patients undergoing colorectal cancer surgery.

Key facts

Study ID

NCT06405776

Run by

West China Hospital

People needed

276

Starts

2023-06-05

Expected to finish

2027-06-01

Last updated by the study team

2024-05-08

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participants were at least 60 years old;
• American Society of Anesthesiologists (ASA) physical status I to III;
• Body-mass index of 18-30 kg/m2;
• Scheduled for elective colorectal surgery.

You may not qualify if…

• Metastases occurring in other distant organs;
• Severe hepatic insufficiency (aspartate aminotransferase or alaninetransaminase or bilirubin >2.5 times the upper limit of normal);
• Renal impairment (creatinine clearance <60 mL/min);
• Cardiac rhythm disorders or systolic heart failure (second-and thirddegree heart block, ejection fraction <50%);
• Allergies to any of the trial drugs; chronic opioid use;
• Inability to comprehend numeric rating scale.

Where it is running

• China — Sichuan, China (enrolling)

Full record on ClinicalTrials.gov

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