FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Running, not enrolling · Phase 2
Conditions studied: Metastatic Castration-resistant Prostate Cancer
In brief
This is an open-label, randomized, multicenter study of FPI-2265 (225Ac-PSMA-I\&T). Patient population is adult participants with PSMA positive mCRPC who have had previous treatment with with 177Lu-PSMA-617 or another 177Lu-PSMA radioconjugate (RC). The purpose of the study is to determine the safety and tolerability, and recommended dose and regiment of FPI-2265.
Key facts
- Study ID
- NCT06402331
- Run by
- Fusion Pharmaceuticals Inc.
- People needed
- 110
- Starts
- 2024-03-05
- Expected to finish
- 2031-01-23
- Last updated by the study team
- 2026-04-08
Who can join
Age: 18 and older. Sex: male. Healthy volunteers: not accepted.
Where it is running
- City of Hope Comprehensive Cancer Center — Duarte, California, United States
- Hoag Health Center Irvine — Irvine, California, United States
- VA Greater Los Angeles Healthcare System — Los Angeles, California, United States
- University of California Los Angeles — Los Angeles, California, United States
- UCSF School of Medicine — San Francisco, California, United States
- Biogenix Molecular, LLC — Miami, Florida, United States
- University of Iowa Hospitals and Clinics — Iowa City, Iowa, United States
- United Theranostics — Glen Burnie, Maryland, United States
- BAMF Health — Grand Rapids, Michigan, United States
- SSM Health Saint Louis University Hospital — St Louis, Missouri, United States
- XCancer — Omaha, Nebraska, United States
- New Mexico Oncology Hematology Consultants Ltd. — Albuquerque, New Mexico, United States
- Laura and Isaac Perlmutter Cancer Center at NYU Langone — New York, New York, United States
- Memorial Sloan Kettering Cancer Center - NYC — New York, New York, United States
- Oregon Health and Science University (OHSU, Knight Cancer Center) — Portland, Oregon, United States
- VA North Texas Health Care System, Nuclear Medicine Service — Dallas, Texas, United States
- The University of Texas Southwestern Medical Center — Dallas, Texas, United States
- U.T. MD Anderson Cancer Center — Houston, Texas, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.