Identifying Wearable Biomarkers to Monitor Dietary Intake

Recruiting now · Not applicable

Conditions studied: Energy Intake, Metabolism, Digestion, Wearables, Dietary Intake Assessment, Healthy Volunteers, Blood Glucose

In brief

Background: Measuring what people eat is a challenge in nutrition research. Traditional methods, like food diaries, rely on self-reporting of individuals, and suffer from poor accuracy and recall bias. Aims: This project aims to identify physiological biomarkers related to food and energy intake, which may be used to develop an objective tool to estimate individuals' food intake in future. Eating behaviours are accompanied by significant physiological changes such as skin temperature, blood oxygen saturation, pulse rate etc. The investigators intend to investigate whether monitoring these physiological changes can help us estimate eating behaviour, such as meal size, eating speed, and duration of meals. Study design: Ten healthy adults will be invited for two study visits at NIHR Imperial Clinical Research Facility. Each visit will last for approximately 2 hr. They will consume a high- and low-calorie meal designed by nutritional researchers in a randomised order. During eating events, the investigators will track their physiological changes via a bedside monitor and wearable sensors. Blood samples will be taken from participants to measure their glycaemic response. Associations between energy load, glycaemic response, and physiological changes will be investigated. Our findings may promote an accelerated development of a wearable tool for dietary assessment in future.

Key facts

Study ID

NCT06398340

Run by

Imperial College London

People needed

10

Starts

2024-08-19

Expected to finish

2025-07-31

Last updated by the study team

2025-02-18

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male or female
• Age between 18-65 years (inclusive)
• Body mass index (BMI) of 18-30 kg/m2
• Willingness and ability to give written informed consent.
• Willingness and ability to understand, to participate and to comply with the study requirements

You may not qualify if…

• Outside of specified age and BMI range
• Chronic medical conditions including for eating disorders, diabetes, obesity, hypertension, cancer, acute infectious disease, renal disease, cardiovascular disease, and chronic gastrointestinal condition.
• Taking part in another research study or donating any blood in the last 3 months

Where it is running

• NIHR Imperial College London Clinical Research Facility — London, United Kingdom (enrolling)

Full record on ClinicalTrials.gov

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