Idiopathic Generalized Epilepsy Syndromes

Recruiting now

Conditions studied: Epilepsy, Epilepsy, Idiopathic Generalized

In brief

The idiopathic generalized epilepsies (IGEs) have historically included the syndromes childhood absence epilepsy (CAE), juvenile absence epilepsy (JAE), juvenile myoclonic epilepsy (JME), and epilepsy with generalized tonic-clonic seizures alone (GTCA). Recognition of the IGEs is important for clinical care, as it informs diagnosis, prevents unnecessary investigation, allows optimal selection of anti-seizure medications (ASMs), and provides prognostic guidance. According to the new ILAE definition in 2022, the study aims to describe the clinical features, electroencephalographic, imaging findings and long-term prognosis.

Key facts

Study ID

NCT06388174

Run by

Shen Chun-Hong

People needed

200

Starts

2023-01-01

Expected to finish

2033-12-31

Last updated by the study team

2025-08-27

Who can join

Age: 4 and older, up to 40. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients are consecutively and prospectively enrolled from epilepsy center, with newly diagnosed epilepsy or established epilepsy.
• Patients have a diagnosis of idiopathic generalized epilepsy (IGE), according to the 2022 diagnostic criteria.
• Comprehensive clinical information is collected, and 24 hour video-electroencephalography is performed.
• Sign the informed consent forms.

You may not qualify if…

• Other epilepsy syndromes are considered during follow-up, such as genetic generalized epilepsy.
• Lost to follow-up

Where it is running

• 2nd Affiliated Hospital, School of Medicine, Zhejiang University, China — Hangzhou, Zhejiang, China (enrolling)

Full record on ClinicalTrials.gov

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