The Project of Gestational Hypertension and Preeclampsia Screening and Prevention Center

Recruiting now

Conditions studied: Preeclampsia, Maternal Deaths

In brief

Preeclampsia is the main cause of illness and death in pregnant women and fetuses. Currently, there is no effective treatment for preeclampsia in clinical practice, and the fundamental treatment is still termination of pregnancy and placental delivery. Therefore, early prediction of preeclampsia and targeted strengthening of high-risk pregnant women supervision, early intervention and diagnosis and treatment can greatly reduce the serious obstetric complications and perinatal maternal and fetal deaths caused by preeclampsia, which has significant social and clinical significance.

Key facts

Study ID

NCT06383858

Run by

The Third Affiliated Hospital of Guangzhou Medical University

People needed

50000

Starts

2023-08-01

Expected to finish

2028-12-31

Last updated by the study team

2024-09-19

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• 1) Pregnant women who have been screened for pre-eclampsia risk according to the clinical risk factors listed in NICE guidelines (2019);
• 2) Based on the authoritative guideline of Figo and the consensus of experts in China, pregnant women who routinely use maternal factor +MAP＋PLGF±UtA-PI in the first trimester or PLGF or sFlt-1/PLGF in the second and third trimesters to assess the risk of preeclampsia.
• 3) Meet any of the above conditions, join the group voluntarily, and sign the informed consent form.

You may not qualify if…

• 1) Severe fetal malformation or abnormality (no fetal heartbeat);
• 2) Those who regularly use aspirin before joining the group;
• 3) There are obvious other abnormal signs, laboratory tests or other clinical d• iseases, which are judged by the researcher to be not suitable for participating in researchers;
• 4) Unable to obtain follow-up and delivery information.

Where it is running

• FANG HE — Guangzhou, Guangdong, China (enrolling)

Full record on ClinicalTrials.gov

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