Childhood Early Oral Aging Syndrome: Prevalence, Etiological Factors, and Consequences on Occlusion
Recruiting now
Conditions studied: Aging
In brief
The Early Oral Aging Syndrome (EOAS) is a broad concept concerning changes in oral health caused by systemic diseases of different origins, which are related to the current lifestyle in the pediatric population. Enamel defects associated with intrinsic and extrinsic factors promote the acceleration of dental structure loss in an early manner, causing impairment of function, aesthetics, and quality of life. In this context, this study aims to identify the prevalence of early childhood tooth wear and its severity using the Early Childhood Oral Aging Syndrome (EOAS) index as a diagnostic and epidemiological survey instrument, considering current alterations found in the pediatric population and verifying possible factors associated with each severity level. Participants aged 3 to 6 years old, enrolled in the pediatric dentistry clinic of the University Nove de Julho, will be selected. Children with imperfect amelogenesis and dentinogenesis, genetic syndromes, and undergoing orthodontic treatment will be excluded from the research. A questionnaire on general health, sleep quality, nutrition, hygiene habits, and parafunctional habits will be administered. Subsequently, a clinical examination will be conducted using the new Early Childhood Oral Aging Syndrome (EOAS) index with scores ranging from 0 to 3 to assess dental wear and dental management, and scores I to III that should be used concomitantly in cases of enamel defects presence, in addition to measuring the Vertical Dimension of Occlusion (VDO). EOAS scores will be computed and statistically analyzed for deciduous dentition with a significance level of P\<0.05.
Key facts
- Study ID
- NCT06381414
- Run by
- University of Nove de Julho
- People needed
- 183
- Starts
- 2024-05-01
- Expected to finish
- 2025-06-20
- Last updated by the study team
- 2024-11-18
Who can join
Age: 3 and older, up to 6. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Children from three to six years of age with complete deciduous teeth;
- Children regularly enrolled for dental care at the Uninove pediatric dentistry clinic
You may not qualify if…
- Children with amelogenesis or dentinogenesis imperfecta
- Children undergoing orthodontic treatment
- Children with a genetic syndrome
Where it is running
- Nove de Julho University — São Paulo, São Paulo, Brazil (enrolling)
Full record on ClinicalTrials.gov
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