Developmental and Epileptic Encephalopathy of Genetic Etiology: Natural History Through Reuse of Clinical Data
Recruiting now
Conditions studied: Developmental and Epileptic Encephalopathy
In brief
Developmental and Epileptic Encephalopathy (DEE) are a heterogeneous group of neurodevelopmental disorders linked to both epilepsy and its underlying etiology, independently of epileptiform activity. The creation of a database with retrospective follow-up of a large number of patients on a national scale will enable better knowledge of specific biomarkers, and thus a better classification and understanding of the natural evolution of DEE according to their etiology. This will enable better, more personalized therapeutic management of patients, depending on etiology and the presence or absence of these biomarkers. The investigators will also be able to draw up management recommendations, which are currently non-existent.
Key facts
- Study ID
- NCT06380192
- Run by
- Imagine Institute
- People needed
- 400
- Starts
- 2024-10-31
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2025-06-29
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosis of Developmental and Epileptic Encephalopathy
- Registered with or benefiting from a social security scheme.
You may not qualify if…
- Opposition of the patient or his/her parents to the re-use of data in the context of this study
- Person subject to a safeguard of justice measure
Where it is running
- Necker-Enfants Malades Hospital — Paris, France (enrolling)
- CH Angers — Angers, France
- Chu Besancon — Besançon, France
- CHU Bordeaux — Bordeaux, France
- CHRU Brest — Brest, France
- CHU Clermont-Ferrand — Clermont-Ferrand, France
- CHU Grenoble — Grenoble, France
- CHU Lille — Lille, France
- CHU Limoges — Limoges, France
- CHU Lyon HCL — Lyon, France
- Assistance Publique Hopitaux de Marseille — Marseille, France
- CHU de Nancy — Nancy, France
- Hopitaux Pediatriques de Nice CHU Lenval — Nice, France
- CHU Pitié Salpétrière — Paris, France
- CHU Robert Debré — Paris, France
- Hôpital Armand Trousseau — Paris, France
- Chu Reims — Reims, France
- CHU Rennes — Rennes, France
- CHU Strasbourg — Strasbourg, France
- CHU Toulouse — Toulouse, France
- CHRU Tours — Tours, France
- CHU Amiens — Amiens, France
- Hôpital André Mignot (CH Versailles) — Versailles, France
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.