Investigating the Plasticity of Human Predictive Coding Through Neuromodulation

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Human Brain and Cognition

In brief

The hypothesis of the study is to investigate how different trm (tES) methods (transcranial Alternating Current Stimulation, tACS, and transcranial Random Noise Stimulation, tRNS) applied at different stimulation frequencies and networks can modulate the predictive mechanisms in human perception and cognition. This is an interventional, monocentric, cross-sectional randomized, single-blinded study on healthy adult volunteers, recruited through online advertisements, flyers and oral transmission. Volunteers will be recruited from the general population of young adults.

Key facts

Study ID

NCT06374433

Run by

Università Vita-Salute San Raffaele

People needed

210

Starts

2024-06-13

Expected to finish

2026-12-31

Last updated by the study team

2024-06-14

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Participant is willing and able to give informed consent for participation in the study.
• Aged 18-35 years.
• Normal or corrected to normal vision, as per anamnestic investigation.

You may not qualify if…

• Participants with a diagnosis of epilepsy (as per anamnestic investigation).
• Participants with major neurological disorders (as per anamnestic investigation).
• Participants that are currently under psychopharmacological treatment with tricyclic antidepressants (as per anamnestic investigation).
• Participants with metal implants in the brain, pacemakers, brain stimulators, cochlear implants (as per anamnestic investigation).

Where it is running

• Università Vita-Salute San Raffaele — Milan, Italy (enrolling)

Full record on ClinicalTrials.gov

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