Resistance Training and Corticospinal Excitability in Multiple Sclerosis

Recruiting now · Not applicable

Conditions studied: Multiple Sclerosis

In brief

The goal of the present study is to investigate effects of progressive resistance training on central nervous system functioning (corticospinal excitability (CSE)) and walking capacity in persons with multiple sclerosis (pwMS). A total of 54 pwMS will be enrolled and randomized into 1 of 3 groups: high dose resistant training (RT), low dose RT, and waitlist control.

Key facts

Study ID

NCT06374108

Run by

University of Aarhus

People needed

54

Starts

2024-05-01

Expected to finish

2026-05-31

Last updated by the study team

2024-12-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years
• MS diagnosis according to the McDonald diagnostic criteria
• Shows impairments in walking capacity
• Ability to self transport to test and exercise

You may not qualify if…

• Pregnancy
• Neurological or other comorbidities that affects the nervous system
• Relapse within the past 2 months
• Pacemaker or metallic implants
• Hypertension (medically unregulated)
• Participation in structured RT over the past 3 months (≥ 2 sessions/week).

Where it is running

• Department of Public Health — Aarhus, Central Jutland, Denmark (enrolling)
• Department of Nutrition, Exercise and Sports, University of Copenhagen — Copenhagen, Copenhagen N, Denmark (enrolling)

Full record on ClinicalTrials.gov

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