REtinal Markers In Neuroinflammatory Diseases ("REMIND")

Recruiting now

Conditions studied: Multiple Sclerosis, Neuroinflammatory Diseases

In brief

The goal of this observational study, including patients with Multiple Sclerosis, patients with other neuroinflammatory diseases and healthy controls, is to determine the predictive value of retinal markers in predicting disease progression. Participants complete a questionnaire and undergo various non-invasive retinal routine clinical examinations.

Key facts

Study ID

NCT06369766

Run by

University Hospital, Basel, Switzerland

People needed

500

Starts

2024-01-31

Expected to finish

2029-02-01

Last updated by the study team

2025-05-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• All groups:
• Age >18 years old
• Patients with Multiple Sclerosis:
• Diagnosis of Multiple Sclerosis, according to the last revisions of the McDonald Criteria (2017)
• Patients with other neuroinflammatory diseases:
• Diagnosis of Neuromyelitis optica spectrum disorder or Myelin oligodendrocyte glycoprotein antibody disease or other neuroinflammatory disorders other than Multiple Sclerosis

You may not qualify if…

• All groups:
• Inability to undergo Optical Coherence Tomography (OCT) and/or retinal vessel imaging (e.g. severe nystagmus that prevents eye fixation on both eyes)
• Presence of any ocular pathology that may interfere with the validity of the OCT/retinal vessel analysis (cataracts, glaucoma, history of refractive defects >6 D etc.).
• Pregnancy and Lactation
• Healthy Controls
• History of other neurological conditions: participants with a history of other significant neurological conditions that might interfere with the assessment or interpretation of the signs and symptoms will be excluded (e.g. confirmed Stroke, Acute disseminated encephalomyelitis, Chronic inflammatory Demyelinating Disease, Polyneuropathy, etc.)

Where it is running

• University Hospital Basel, Department of Neurology — Basel, Switzerland (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.