How Much Does Reduced Dosing of Latanoprost and Dorzolamide-timolol Affect Pressure?

Stopped early · Phase 4

Conditions studied: Glaucoma, Open-Angle, Glaucoma; Drugs

In brief

IOP effect of half-dose latanoprost dorzolamide-timolol will be compared to full dose. Further comparison will be made timolol-brimonidine-dorzolamide-bimatoprost. Dry eye effects of the different treatments will be assessed.

Key facts

Study ID

NCT06369077

Run by

CT Glaucoma Associates

People needed

36

Starts

2024-04-22

Expected to finish

2024-07-30

Last updated by the study team

2024-08-23

Who can join

Age: 25 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adult glaucoma patients who are taking drops: dor-tim and Latanoprost Ophthalmic Solution 0.005% (Lat) and come in for an appointment during the trial period

You may not qualify if…

• Patients who had an SLT or glaucoma procedure or surgery within 3 months of enrollment will be excluded. Other exclusion criteria include the logistical inability to follow up with the trial, the inability to relax eye muscles for an accurate tonometry measurement, and the inability to instill medications.
• The final determination to be included in the study will be made by the Physician on the day of the appointment.

Where it is running

• CT Glaucoma Associates — Norwalk, Connecticut, United States

Full record on ClinicalTrials.gov

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