An Economic and Relationship-strengthening Intervention to Reduce Alcohol Use in Malawi

Recruiting now · Not applicable

Conditions studied: HIV/AIDS, Alcohol Abuse

In brief

With a full-scale randomized control trial, the investigators will evaluate the efficacy and cost effectiveness of Mlambe, an economic and relationship-strengthening intervention that provides incentivized saving accounts, financial literacy training, and relationship skills education to break the cycle of poverty around drinking, strengthen couple support and communication, and reduce heavy drinking among HIV-affected married couples with a partner who drinks alcohol in Malawi.

Key facts

Study ID

NCT06367348

Run by

University of California, San Francisco

People needed

500

Starts

2025-02-14

Expected to finish

2028-05-01

Last updated by the study team

2026-05-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• In a married or cohabitating union
• Have at least one partner with a positive AUDIT-C screen in prior 3 months
• Must also currently be on ART for at least 6 months
• Must have disclosed their HIV status to their partner

You may not qualify if…

• Severe intimate partner violence reported in previous 3 months and/or fear that safety would be at risk by participation in the study (reported at screening). Couples who participated in Mlambe's pilot study will also be excluded.

Where it is running

• Invest in Knowledge Initiative (IKI) — Zomba, Malawi (enrolling)

Full record on ClinicalTrials.gov

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