oPen Versus RobotIc retrOmuscular Repair in Medium to Large Ventral Hernias

Recruiting now · Not applicable

Conditions studied: Ventral Hernia, Incisional Hernia, Abdominal Wall Defect

In brief

This study investigates on the effect of two different operative techniques to treat large abdominal wall defects. The goal of this clinical trial is to learn if the minimally-invasive, robotically-assisted ventral hernia repair (RVHR) leads to a better outcome than the open ventral hernia repair (OVHR). The main questions it aims to answer are: length of stay after the operation rate of complications rate of recurrence and reoperations quality of life. Participants will: Either be operated using the RVHR or OVHR will be followed up either in person or via email / phone call at day 7, day 30, 6 months, 1, 3 and 5 years after the surgery to asses the above-stated main and some more outcomes.

Key facts

Study ID

NCT06364306

Run by

University Hospital, Basel, Switzerland

People needed

140

Starts

2026-07-14

Expected to finish

2033-12-31

Last updated by the study team

2026-07-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient age >18 years
• Informed consent obtained
• Transverse diameter of ventral hernia >4cm - 15cm
• Eligible to open and minimally-invasive surgery according to preoperative anaesthetic assessment

You may not qualify if…

• precedent hernia treatment with mesh placement in the retromuscular space
• precedent anterior or posterior component separation or transversus abdominis release (TAR)
• active wound infection
• current cancer diagnosis
• presence of ileostomy, colostomy or ileal conduit
• liver disease defined by the presence of ascites
• end-stage renal disease requiring dialysis
• need of an emergency surgery
• pregnancy
• Criteria for participating surgeons Each participating surgeon has performed 20 or more OVHR and RVHR.

Where it is running

• University Hospital Basel — Basel, Canton of Basel-City, Switzerland (enrolling)
• Klinikum Kempten — Kempten (Allgäu), Bavaria, Germany
• Spital Oberwallis, Visp — Visp, Valais, Switzerland

Full record on ClinicalTrials.gov

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