Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health
Status unconfirmed · Not applicable · Has a placebo group
Conditions studied: Pre Hypertension, Hypertension
In brief
The investigators long-term goal is to better understand novel interventions to promote cardiovascular health in humans. The goal of the proposed research is to investigate whether there is sex-specificity in the effects of dietary capsaicin on mechanisms regulating nitric oxide (NO) bioavailability, its effect on key markers of cardiovascular (CV) health, including BP, macro- and microvascular function, and arterial stiffness. This knowledge will provide critical insight into the effects of dietary capsaicin on CV health and will guide future trials.
Key facts
- Study ID
- NCT06363305
- Run by
- Skidmore College
- People needed
- 80
- Starts
- 2024-07-08
- Expected to finish
- 2025-12-31
- Last updated by the study team
- 2024-07-10
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- relatively healthy (other than elevated blood pressure) non-smoking men and women over the age of 18 from the local community
You may not qualify if…
- Women who are without a period (not due to a birth control method, intrauterine device or menopause), are pregnant, attempting to conceive, or are breastfeeding will be excluded.
- uncontrolled hypertension
- Anyone with severe illness or compromised or suppressed immune system (e.g. taking immune suppressants, chronic viral infection or treatment).
- Any participants with excessive sensitivity to spicy foods or fiber (psyllium husk) will be excluded
- Participants with food allergies will be excluded
- Participants who have difficulty swallowing or swallowing pills may be excluded.
- Participants who suffer from heartburn, hiatal hernia, gastritis, or peptic ulcer disease may be excluded.
Where it is running
- Skidmore College — Saratoga Springs, New York, United States (enrolling)
Full record on ClinicalTrials.gov
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