Linking Somatic Mutation Rate With Baseline Exposure in East Palestine
Recruiting now · Not applicable
Conditions studied: Somatic Mutation
In brief
The goal of this study is to This research team is conducting this study to develop methods to measure the biological impact of exposure to the chemicals released following the February 3, 2023 train derailment on residents of East Palestine, Ohio, and surrounding communities. The main question it aims to answer is: * What biological impact will be measured based on DNA damage? * In participants who provide a biospecimen, how are biomarker changes related to proximity to the derailment and variations in residents' health histories and behaviors? Participants will: * Complete a brief survey asking about experiences related to the February 3, 2023 train derailment, health experiences, and concerns following the derailment, and background information regarding health history. * Possibly contribute biospecimens such as blood, spit, hair, and/or toenail clippings. * Receive communication about study updates and future research opportunities. * A total of 40 study participants will be recruited to participate in a 90-minute interview. The interviews will be video and audio recorded.
Key facts
- Study ID
- NCT06357845
- Run by
- Case Comprehensive Cancer Center
- People needed
- 500
- Starts
- 2024-08-16
- Expected to finish
- 2026-09-30
- Last updated by the study team
- 2026-03-16
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Residence on February 3rd, 2023 in Columbiana County, Ohio, Mahoning County, Ohio, Beaver County, PA, or Lawrence County, PA.
- Current residence in the United States.
You may not qualify if…
- Address provided for February 3rd, 2023 not in Columbiana County, Ohio, Mahoning County, Ohio, Beaver County, PA, or Lawrence County, PA
- Invalid address provided for February 3rd, 2023 residence.
Where it is running
- Case Western Reserve University, Case Comprehensive Cancer Center — Cleveland, Ohio, United States (enrolling)
Full record on ClinicalTrials.gov
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