The Relationship Between Controlling Risk Factors and Cerebral Haemodynamics in Lacunar Stroke

Recruiting now

Conditions studied: Lacunar Stroke

In brief

The goal of this observational study is to look at differences in brain blood flow before and after management of risk factors such as high blood pressure and diabetes in patients with lacunar stroke. Participants will be asked to undergo a simple brain blood flow assessment at their initial appointment, whereby they will be asked to sit and stand twice. The patients will then be asked for a follow-up assessment 4 weeks after, identical to the first. This will allow us to look at any changes in brain blood flow from before management of risk factors and 4 weeks after management of risk factors.

Key facts

Study ID

NCT06354881

Run by

University of Leicester

People needed

75

Starts

2024-05-02

Expected to finish

2026-03-01

Last updated by the study team

2025-03-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged between 18-120 years.
• Diagnosis of lacunar stroke syndrome.
• New diagnosis or known diagnosis of hypertension and/or diabetes.

You may not qualify if…

• Those who lack capacity can have a personal consultee consent to the study if they can still perform study requirements such as the sit-stand manoeuvre. Those who either cannot perform the manoeuvre or do not have a personal consultee to allow them to consent, are not able to take part.
• Those with poorly controlled medical comorbidities affecting cerebral haemodynamics. (eg., heart failure).

Where it is running

• University Hospitals of Leicester NHS Trust — Leicester, Leicestershire, United Kingdom (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.