A Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM)
Running, not enrolling · Phase 2
Conditions studied: Hypertrophic Cardiomyopathy
In brief
This study is being conducted in order to understand the safety and effects of different doses of EDG-7500 as a single dose in adults with obstructive hypertrophic cardiomyopathy (oHCM) and as multiple doses in adults with obstructive or nonobstructive hypertrophic cardiomyopathy (nHCM).
Key facts
- Study ID
- NCT06347159
- Run by
- Edgewise Therapeutics, Inc.
- People needed
- 79
- Starts
- 2024-04-11
- Expected to finish
- 2027-12-01
- Last updated by the study team
- 2026-07-31
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of California, San Francisco — San Francisco, California, United States
- Stanford University Hospital / Stanford Health Care — Stanford, California, United States
- Emory Clinic — Atlanta, Georgia, United States
- Massachusetts General Hospital — Boston, Massachusetts, United States
- Brigham and Womens Hospital — Boston, Massachusetts, United States
- Lahey Hospital and Medical Center — Burlington, Massachusetts, United States
- Michigan Medicine - Michigan Clinical Research Unit — Ann Arbor, Michigan, United States
- Saint Luke's Hospital of Kansas City — Kansas City, Missouri, United States
- Morristown Medical Center (Atlantic Health System) — Morristown, New Jersey, United States
- North Shore University Hospital — Manhasset, New York, United States
- NYU Langone Health Medical Center - HCM Program Office (Study open to existing NYU patients only) — New York, New York, United States
- Sanger Heart and Vascular Institute — Charlotte, North Carolina, United States
- Duke Health Center Arringdon — Morrisville, North Carolina, United States
- The Lindner Research Center at Christ Hospital — Cincinnati, Ohio, United States
- University Hospitals Cleveland Medical Center — Cleveland, Ohio, United States
- Cleveland Clinic — Cleveland, Ohio, United States
- Oregon Health & Science University (OHSU) — Portland, Oregon, United States
- Hospital of the University of Pennsylvania (University of Pennsylvania School of Medicine) — Philadelphia, Pennsylvania, United States
- Medical University of South Carolina — Charleston, South Carolina, United States
- University of Virginia Heart and Vascular Center Fontaine — Charlottesville, Virginia, United States
- Virginia Mason Medical Center — Seattle, Washington, United States
Full record on ClinicalTrials.gov
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