NRM on Vascular Perfusion in Healthy Adults
Enrolling by invitation · Not applicable · Has a placebo group
Conditions studied: Vascular Stiffness
In brief
The purpose of this study is to better understand the effects of nicotinamide riboside supplement in overall cardiovascular health in healthy adults.
Key facts
- Study ID
- NCT06345443
- Run by
- Mayo Clinic
- People needed
- 200
- Starts
- 2024-11-25
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2026-03-18
Who can join
Age: 35 and older, up to 70. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- >= 35 and <=70
- Provides consent to participate in the study
- Not pregnant at time of consent
- Understands and agrees to follow all study procedures and limitations
- Have no contraindicating comorbid health condition as determined by the clinical investigators
You may not qualify if…
- Pregnant, nursing, or trying to conceive
- BMI Restrictions: <35
- Allergy or sensitivity to study agent ingredients
- Hypertension treated with medication
- Use of natural health products containing nicotinamide riboside, quercetin, trans-resveratrol, or betaine anhydrous within 7 days prior to randomization and during the course of the study.
- Surgery planned during the course of the trial
- History or past diagnosis of chronic diseases, unstable medical conditions, blood/bleeding disorders or stroke
- History or current diagnosis of cancer (except for successfully treated basal cell carcinoma diagnosed less than 5 years prior to screening or cancer in full remission more than 5 years after diagnosis.
- Abnormal blood chemistries for renal or liver function (defined as 1 standard deviation outside of the normal range), alcohol dependence, uncontrolled thyroid disease, severe obesity (body mass index >40 kg m-2), or weight stable for at least 3 months prior to enrolling in the study (defined as >2 kg change in body mass).
- An unstable medical or mental health condition as determined by the physician investigator.
Where it is running
- Mayo Clinic in Rochester — Rochester, Minnesota, United States
Full record on ClinicalTrials.gov
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