Early Detection of Advanced Adenomas and Colorectal Cancer
Recruiting now
Conditions studied: Colorectal Cancer, Colorectal Neoplasms, Colorectal Polyp, Colorectal Adenocarcinoma, Colorectal Disorders, Colorectal Dysplasia, Colorectal Cancer Stage I, Colorectal Cancer Stage II, Colorectal Cancer Stage III, Colorectal Cancer Stage IV, Colorectal Neoplasms Malignant, Colorectal Serrated Adenocarcinoma, Colorectal Adenoma With Severe Dysplasia, Colorectal Adenoma With Mild Dysplasia, Colorectal Adenoma With Moderate Dysplasia, Colorectal Adenoma and Carcinoma 1, Colorectal Adenomatous Polyp, Colorectal Adenocarcinoma Metastatic in the Liver
In brief
This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.
Key facts
- Study ID
- NCT06342440
- Run by
- City of Hope Medical Center
- People needed
- 2000
- Starts
- 2020-03-15
- Expected to finish
- 2028-06-18
- Last updated by the study team
- 2026-07-07
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- All individuals included in the study need to have had a colonoscopy at the time of blood sampling.
- Received standard diagnostic and staging (as necessary) procedures as per local guidelines, and at least one sample was drawn before receiving any curative-intent treatment.
- Received standard pathological and endoscopic diagnosis and assessment for cohort assignment.
You may not qualify if…
- Hereditary colorectal cancer syndromes (identified through genetic testing).
- Inflammatory bowel diseases.
- Lack of written informed consent.
Where it is running
- City of Hope Medical Center — Monrovia, California, United States (enrolling)
- University of California San Diego — San Diego, California, United States (enrolling)
- The First Affiliated Hospital of Dalian Medical University — Dalian, China (enrolling)
- IRCCS San Raffaele — Milan, Italy (enrolling)
- Mie University — Mie, Japan (enrolling)
- Barcelona University — Barcelona, Spain (enrolling)
Full record on ClinicalTrials.gov
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