Relationship Between Breathing and Attention in Children With Ondine Syndrome

Recruiting now

Conditions studied: Ondine Syndrome, Congenital Central Hypoventilation Syndrome (CCHS)

In brief

Congenital central hypoventilation syndrome (CCHS) is a rare disorder of autonomic and respiratory regulation that alters oxygen delivery to the brain. CCHS patients are at risk for broad neurocognitive deficits. Patients retain ventilatory activity when awake through a respiratory-related cortical network but the need to mobilise cortical resources to breathe lead to breathing-cognition interferences during cognitive tasks. The purpose of this study is to assess the relationship between breathing pattern and attention in CCHS children

Key facts

Study ID

NCT06337149

Run by

Assistance Publique - Hôpitaux de Paris

People needed

20

Starts

2024-02-29

Expected to finish

2026-09-01

Last updated by the study team

2024-03-29

Who can join

Age: 6 and older, up to 16. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• children with CCHS (Ondine Syndrome) and IQ > 70, age from 6 to 16 years old, french speaking, informed consent signed by both parents and oral agreement in principle given by the subject.

You may not qualify if…

• IQ < 70

Where it is running

• Robert Debre Hospital — Paris, France (enrolling)

Full record on ClinicalTrials.gov

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