BEST-RPP Pilot: Screening for Esophageal Cancer in Rural Oregon Without an Endoscopy

Running, not enrolling

Conditions studied: Esophageal Cancer

In brief

Recent advancements in swallowable esophageal cell-collection devices (SECD) offer a safe, minimally invasive, accurate, and low-cost alternative to esophageal screening without the need for an upper endoscopy. The BEST-RPP study aims to evaluate the acceptability and feasibility of using this novel approach to screen for Barrett's Esophagus (BE) and Esophageal Carcinoma (EAC) in rural primary care clinic settings in Oregon.

Key facts

Study ID

NCT06335966

Run by

OHSU Knight Cancer Institute

People needed

110

Starts

2024-09-11

Expected to finish

2026-12-30

Last updated by the study team

2026-03-17

Who can join

Age: 50 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Signed informed consent
• Willing and able to comply with the protocol
• Live in a rural area
• Chronic GERD Dx
• 3 or more of the following risk factors: Male, age >50 years White race Tobacco smoking Obesity Family history of BE or EAC in a first-degree relative

Where it is running

• OHSU Knight Cancer Institute — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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