Intraoperative Electrical Stimulation to Improve Nerve Grafting Outcome

Recruiting now · Not applicable

Conditions studied: Facial Paralysis

In brief

A research study to find out if brief intraoperative electrical stimulation therapy improves nerve regeneration and smile outcomes following two-stage cross face nerve graft facial reanimation surgery.

Key facts

Study ID

NCT06335719

Run by

The Cleveland Clinic

People needed

20

Starts

2023-03-01

Expected to finish

2026-12-31

Last updated by the study team

2025-07-30

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients 18-80 years-old with unilateral facial paralysis who are candidates for two- stage CFNG smile reanimation surgery (i.e. CFNG-driven free gracilis muscle transfer (FGMT) or dual innervation FGMT).
• Agree to participate in the study.

You may not qualify if…

• Bilateral facial paralysis
• Age less than 18 years-old or older than 80 years-old
• Comorbid medical condition preventing two-stage CFNG surgery

Where it is running

• Cleveland Clinic Foundation — Cleveland, Ohio, United States (enrolling)

Full record on ClinicalTrials.gov

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